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Alto Neuroscience

ANRO
Biotechnology · Healthcare
Price
$27.54
+0.21 (+0.77%)
Market Cap
$966.5M
Exchange
New York Stock Exchange
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+12.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 25.6M (2021) → 28.9M (2025)

Alto Neuroscience is a biotechnology company focused on developing drugs to treat mental health conditions like depression, schizophrenia, and post-traumatic stress disorder. Instead of using a one-size-fits-all approach, the company uses brain biology data — such as brain wave patterns and biomarkers — to match specific patients to specific drugs. Its customers are patients and eventually healthcare providers, and it operates in the psychiatric drug development industry.

Alto Neuroscience makes no revenue yet, as it is a clinical-stage company spending money to run drug trials before any product is approved or sold. It is based in the United States and is relatively small, with a market cap around $1 billion. Its main competitive edge is its "precision psychiatry" platform, which aims to improve the odds that a drug works by targeting the right patients from the start. The biggest risk is that its drug candidates could fail in clinical trials, which would significantly set back the business.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

Revenue data limited

EPS Growth

-42.9% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$46M/ year

Flat (-3% vs prior year)

Steady R&D investment year-over-year

Insider Activity

9.6%ownership

Insiders own a meaningful stake in the company

Cash Runway

~2 years

$264M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$264M cash & investments at current burn rate

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
N/A
Data not available
Operating Margin
N/A
Data not available
ROCE
-10.9%
Weak — -10.9% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
N/A
Data not available
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
N/A
Data not available

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Stability

Debt / Equity
0.02
Conservative — low debt load (0.02)
Interest Cover
22.72x
Comfortably covers interest (22.7x)

Interest coverage above 8. Profits cover interest many times over.

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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