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Ascendis Pharma A/S

ASND
35
Biotechnology · Healthcare
Price
$261.00
+1.20 (+0.46%)
Market Cap
$16.21B
Exchange
NASDAQ
Winston Score
35
Winston is serious
Below-average fundamentals — multiple weak pillars.

Share count rising — dilution

+10.7% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 54.8M (2021) → 60.6M (2025)

Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing therapeutics for unmet medical needs. The company offers SKYTROFA for treating patients with growth hormone deficiency (GHD). It also develops TransCon Growth Hormone (hGH) for pediatric GHD in Japan; TransCon hGH for adults with GHD; TransCon parathyroid hormone for adult hypoparathyroidism; and TransCon CNP for pediatric achondroplasia. In addition, the company develops TransCon toll like receptors 7/8 agonist for intratum

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+148.3% YoY

YoY Growth Rate

Revenue accelerating

EPS Growth

+756.3% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$284M/ year

Declining (-8% vs prior year)

41.0% of revenue

2.3x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

0.9%ownership

Relatively low insider ownership

Cash Runway

~9 years

$573M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

$573M cash & investments at current burn rate

Revenue accelerating

Ascendis Pharma A/S grew revenue 148% year-over-year and the growth rate is speeding up. That's the kind of momentum growth investors look for — the question is whether margins can follow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
91.4%
Premium pricing power — 91.4% gross margin
Operating Margin
10.1%
Modest — 10.1% operating margin
ROCE
1.8%
Weak — 1.8% return on capital

ROIC between 0% and 5%. They earn a few cents back per dollar invested in the business.

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Growth

Sales YoY
+135.3%
Fast-growing sales (135.3% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
2/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
11%
Weak — only 11% of profit becomes cash
FCF Margin
4.9%
Thin free cash flow (4.9%)

FCF margin between 0% and 10%. Some cash from sales, but not a lot.

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Stability

Debt / Equity
1.84
Elevated debt (1.84)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
31.9x
Pricey — P/E 31.9

P/E above the market average. People are paying up for expected growth.

P/E vs Forward
+13.8
GROWING
Earnings expected to grow meaningfully — cheaper on forward P/E (31.9 → 18.1)

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Dividends

Not applicable for this business.
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