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Autolus Therapeutics

AUTL
19
Biotechnology · Healthcare
Price
$1.44
-0.02 (-1.37%)
Market Cap
$383.2M
Exchange
NASDAQ
Winston Score
19
Winston is worried
Weak fundamentals across most pillars.

Share count rising — dilution

+269.2% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 72.1M (2021) → 266.1M (2025)

Autolus Therapeutics is a British biotechnology company that develops cancer treatments using a technology called CAR-T cell therapy. This approach takes a patient's own immune cells, engineers them in a lab to recognize and attack cancer cells, and then puts them back into the patient's body. The company's lead product, Aucatzyl (obecabtagene autoleucel), was approved by the FDA in 2024 to treat a type of blood cancer called B-cell acute lymphoblastic leukemia in adults.

Autolus makes money by selling Aucatzyl to hospitals and cancer treatment centers in the United States, where it is currently launching the product commercially. The company is small, with a market cap around $500 million, and it is still spending far more than it earns, which is typical for early-stage biotech firms. The key growth driver is how quickly Aucatzyl gains adoption among oncologists, while the main risk is that the company may need to raise additional cash to fund operations before reaching profitability.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+191.9% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

-3.8% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$129M/ year

Declining (-19% vs prior year)

170.2% of revenue

9.5x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

9.6%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~6 months

$131M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Short runway — potential dilution ahead through share issuance

Strong grower

Autolus Therapeutics is growing revenue at 192% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
6.3%
Thin — 6.3% gross margin
Operating Margin
-227.0%
Losing money on operations — -227.0%
ROCE
-31.5%
Weak — -31.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
+927.5%
Fast-growing sales (927.5% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-345.5%
Burning cash (-345.5%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.73
Moderate — manageable debt (0.73)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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