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Bicycle Therapeutics

BCYC
27
Biotechnology · Healthcare
Exchange
NASDAQ
Winston Score
27
Winston is worried
Below-average fundamentals — multiple weak pillars.

Bicycle Therapeutics plc, a clinical-stage biopharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics. Its lead product candidate is BT1718, a bicycle toxin conjugate (BTC), which is in Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease. The company's oncology product candidates also comprise BT5528, a BTC that is in a Phase I/II clinical trial targeting EphA2; and BT8009, which is in Phase I/I

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-91.1% YoY

YoY Growth Rate

Revenue declining

EPS Growth

+1.1% YoY

YoY Growth Rate

Slow EPS growth

Insider Activity

11.4%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~2 years

$559M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$559M cash & investments at current burn rate

Revenue declining

Bicycle Therapeutics's revenue is actually shrinking. In a growth stock, that removes the core investment thesis. The low Winston Score here may be warranted — unless there's a turnaround story.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Operating Margin
-7394.5%
Losing money on operations — -7394.5%
ROCE
-11.8%
Weak — -11.8% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
+146.9%
Fast-growing sales (146.9% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-366.3%
Burning cash (-366.3%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
N/A
Data not available
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/A
no trend
Data not available
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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