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Can-Fite BioPharma

CANF
18
Biotechnology · Healthcare
Price
$3.40
+0.08 (+2.41%)
Market Cap
$1.8M
Exchange
New York Stock Exchange American
Winston Score
18
Winston is worried
Weak fundamentals across most pillars.

Share count falling — buybacks

55.3% over 4y

The company has reduced its share count over this period, returning value to shareholders through buybacks.

Diluted shares outstanding: 1.8M (2021) → 824K (2025)

Can-Fite BioPharma is a small Israeli biotechnology company focused on developing drugs that target a protein in the body called the A3 adenosine receptor. Its main drug candidates aim to treat serious diseases like liver cancer, fatty liver disease, and inflammatory conditions such as psoriasis and rheumatoid arthritis. The company does not yet sell approved products to patients — it is still in the clinical trial stage.

Can-Fite earns almost no revenue from product sales and instead funds its research through grants, licensing deals, and partnerships with larger pharmaceutical companies. It operates primarily out of Israel and is listed on both the Tel Aviv Stock Exchange and the Nasdaq in the United States, keeping it a very small, pre-commercial company. The biggest risk it faces is typical for early-stage biotech: if its lead drug candidates fail in clinical trials or cannot attract a major pharma partner, the company could run out of funding before reaching the market.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-36.1% YoY

YoY Growth Rate

Revenue declining

EPS Growth

+36.4% YoY

YoY Growth Rate

Strong earnings growth

R&D Spend

$7M/ year

Rising (+17% vs prior year)

>1,000% of revenue

91.8x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

4.9%ownership

Relatively low insider ownership

Cash Runway

~11 months

$9M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Heavy R&D investment

Can-Fite BioPharma is putting 1653% of revenue into R&D and that number is rising. That's 91.8x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
100.0%
Premium pricing power — 100.0% gross margin
Operating Margin
-2424.8%
Losing money on operations — -2424.8%
ROCE
-43.8%
Weak — -43.8% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
-16.0%
Shrinking sales (-16.0% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-1492.0%
Burning cash (-1492.0%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
N/A
Data not available
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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