CRISPR Therapeutics AG

CRSP

Biotechnology · Healthcare

Price

$47.78

-0.79 (-1.63%)

Market Cap

$4.61B

Exchange

NASDAQ

Winston Score

Winston is worried

Weak fundamentals across most pillars.

Share count rising — dilution

+11.9% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 80.4M (2021) → 89.9M (2025)

CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious diseases using its proprietary Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform. Its CRISPR/Cas9 is a gene editing technology that allows for precise directed changes to genomic DNA. The company has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, oncology, regenerative medicine, and

Winston Score History

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-97.5% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-211.4% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$265M/ year

↓ Declining (-17% vs prior year)

>1,000% of revenue

420.0x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

0.4%ownership

→ Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~11 months

$355M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Short runway — potential dilution ahead through share issuance

Cash watch

CRISPR Therapeutics AG has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin

-6770.8%

Thin — -6770.8% gross margin

Operating Margin

-17912.5%

Losing money on operations — -17912.5%

ROCE

-7.3%

Weak — -7.3% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY

-90.4%

Shrinking sales (-90.4% YoY)

EPS YoY

N/A

Data not available

EPS Consistency

0/8 quarters

Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion

N/A

—

Data not available

FCF Margin

-9855.5%

Burning cash (-9855.5%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity

0.11

Conservative — low debt load (0.11)

Interest Cover

N/A

—

Data not available

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Valuation

P/E Ratio (TTM)

N/M

—

Negative earnings — P/E not meaningful

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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