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Cue Biopharma

CUE
16
Biotechnology · Healthcare
Price
$31.16
+3.37 (+12.13%)
Market Cap
$81.9M
Exchange
NASDAQ
Winston Score
16
Winston is worried
Weak fundamentals across most pillars.

Share count rising — dilution

+202.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 1.0M (2021) → 3.2M (2025)

Cue Biopharma is a small biotech company focused on developing drugs that train the immune system to fight cancer. Its core approach uses engineered proteins called "Immuno-STATs" that are designed to selectively activate certain immune cells without triggering harmful side effects seen with older cancer treatments. The company's main customers would be patients and healthcare providers, and it operates in the competitive oncology drug development space.

Cue Biopharma makes almost no product revenue yet — it earns money primarily through research collaborations and grants while spending heavily to advance its drug candidates through clinical trials. The company is based in the United States and, with a market cap of roughly $100 million, is considered a micro-cap biotech. Its near-100% gross margin reflects the early-stage nature of its limited revenue, but its deeply negative operating margin shows it is burning cash. The central risk is whether its pipeline candidates will succeed in clinical trials, since failure there would severely threaten the company's ability to survive without raising additional capital.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

>+1,000% YoY

YoY Growth Rate

Revenue accelerating

EPS Growth

+78.8% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$38M/ year

Flat (+4% vs prior year)

137.4% of revenue

7.6x the sector average (18%)

Steady R&D investment year-over-year

Insider Activity

0.8%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~4 months

$16M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

Short runway — potential dilution ahead through share issuance

Revenue accelerating

Cue Biopharma grew revenue 1251% year-over-year and the growth rate is speeding up. That's the kind of momentum growth investors look for — the question is whether margins can follow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin
0.0%
Thin — 0.0% gross margin
Operating Margin
-94.1%
Losing money on operations — -94.1%
ROCE
-21.4%
Weak — -21.4% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
+309.6%
Fast-growing sales (309.6% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
2/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-75.2%
Burning cash (-75.2%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.16
Conservative — low debt load (0.16)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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