Day One Biopharmaceuticals

DAWN

Biotechnology · Healthcare

Price

$21.53

+0.00 (+0.00%)

Market Cap

$2.22B

Exchange

NASDAQ

Winston Score

Winston is serious

Below-average fundamentals — multiple weak pillars.

Share count rising — dilution

+66.9% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 62.0M (2021) → 103.4M (2025)

Day One Biopharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops and commercializes targeted therapies for patients with genetically defined cancers. Its lead product candidate is DAY101, an oral brain-penetrant type II pan-rapidly accelerated fibrosarcoma kinase inhibitor that is in Phase II clinical trial for pediatric patients with relapsed/progressive low-grade glioma. The company is also developing Pimasertib, an oral small molecule inhibitor of mitogen-activated prote

Winston Score History

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+83.9% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

+70.0% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$148M/ year

↓ Declining (-35% vs prior year)

93.6% of revenue

5.2x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

31.0%ownership

→ Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~3 years

$197M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

$197M cash & investments at current burn rate

Strong grower

Day One Biopharmaceuticals is growing revenue at 84% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Gross Margin

88.7%

Premium pricing power — 88.7% gross margin

Operating Margin

-51.1%

Losing money on operations — -51.1%

ROCE

-6.2%

Weak — -6.2% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY

+20.6%

Fast-growing sales (20.6% YoY)

EPS YoY

N/A

Data not available

EPS Consistency

0/8 quarters

Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion

N/A

Data not available

FCF Margin

-72.4%

Burning cash (-72.4%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity

0.01

Conservative — low debt load (0.01)

Interest Cover

N/A

—

Data not available

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Valuation

P/E Ratio (TTM)

N/M

Negative earnings — P/E not meaningful

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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