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Dianthus Therapeutics

DNTH
28
Biotechnology · Healthcare
Price
$105.60
+10.25 (+10.75%)
Market Cap
$4.41B
Exchange
NASDAQ
Winston Score
28
Winston is worried
Below-average fundamentals — multiple weak pillars.

Share count rising — dilution

+1000.5% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 3.4M (2021) → 37.8M (2025)

Dianthus Therapeutics, Inc. operates as a clinical-stage biotechnology company that designs, develops, and delivers novel monoclonal antibodies for people living with severe autoimmune and inflammatory diseases. It develops DNTH103 that is in phase 1 clinical trails in patients with generalized myasthenia gravis, multifocal motor neuropathy, and chronic inflammatory demyelinating polyneuropathy. Dianthus Therapeutics, Inc. was incorporated in 2015 and is based in New York, New York.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-60.2% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-3.7% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$146M/ year

Rising (+75% vs prior year)

>1,000% of revenue

397.4x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

30.2%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~5 years

$628M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

$628M cash & investments at current burn rate

Heavy R&D investment

Dianthus Therapeutics is putting 7153% of revenue into R&D and that number is rising. That's 397.4x the sector average. With 5+ years of cash runway, they have time to let it pay off.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
83.6%
Premium pricing power — 83.6% gross margin
Operating Margin
-10050.3%
Losing money on operations — -10050.3%
ROCE
-3.9%
Weak — -3.9% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
-79.5%
Shrinking sales (-79.5% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
2/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-9766.8%
Burning cash (-9766.8%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.00
Conservative — low debt load (0.00)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/A
Data not available
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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