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Dyadic International

DYAI
16
Biotechnology · Healthcare
Price
$1.26
+0.07 (+5.88%)
Market Cap
$45.9M
Exchange
NASDAQ Capital Market
Winston Score
16
Winston is worried
Weak fundamentals across most pillars.

Share count rising — dilution

+17.2% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 27.8M (2021) → 32.6M (2025)

Dyadic International is a small biotechnology company that develops technology to help make medicines faster and cheaper. Its main product is a platform called C1, which uses a fungus to produce large amounts of proteins — the building blocks used in vaccines, antibodies, and other biological drugs. The company licenses this technology to pharmaceutical and biotech companies that want a more efficient way to manufacture their medicines.

Dyadic earns money primarily through research collaborations, licensing agreements, and grants rather than selling finished drugs itself. It operates mainly in the United States but partners with organizations around the world, including research institutions and drug developers. The company is very small, with a market cap near zero and deep operating losses, meaning it spends far more than it earns. The key growth driver is whether larger pharmaceutical partners adopt the C1 platform at scale, but the main risk is that the company may run out of funding before that happens.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+506.7% YoY

YoY Growth Rate

Revenue accelerating

EPS Growth

+26.3% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$2M/ year

Rising (+5% vs prior year)

174.8% of revenue

9.7x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

25.7%ownership

Insiders own a meaningful stake in the company

Cash Runway

~10 months

$7M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Revenue accelerating

Dyadic International grew revenue 507% year-over-year and the growth rate is speeding up. That's the kind of momentum growth investors look for — the question is whether margins can follow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
28.7%
Modest — 28.7% gross margin
Operating Margin
-172.1%
Losing money on operations — -172.1%
ROCE
-41.2%
Weak — -41.2% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
-11.0%
Shrinking sales (-11.0% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-192.1%
Burning cash (-192.1%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
N/A
Data not available
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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