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Fulcrum Therapeutics

FULC
Biotechnology · Healthcare
Price
$3.65
+0.15 (+4.29%)
Market Cap
$197.5M
Exchange
NASDAQ
Winston Score
Winston looking sleepy
No score yet — Winston is napping.
We couldn’t gather enough financial data to score this stock reliably.

Share count rising — dilution

+79.2% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 35.4M (2021) → 63.4M (2025)

Fulcrum Therapeutics is a small biotech company that works on developing new medicines for rare genetic diseases. Its main focus is on conditions caused by genes that are not working the way they should. The company's lead drug candidate, losmapimod, is being tested as a treatment for facioscapulohumeral muscular dystrophy, or FSHD, a rare muscle-wasting disease that currently has no approved treatments.

Fulcrum does not yet sell any products, so it earns no revenue from product sales. Instead, it funds its research through partnerships, grants, and by raising money from investors. The company operates primarily in the United States and is considered a clinical-stage biotech, meaning it is still running clinical trials rather than generating commercial sales. Its biggest risk is straightforward: if losmapimod fails in late-stage trials, the company loses its primary path to becoming a viable business, and its cash runway will determine how much time it has to find another way forward.

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

YoY Growth Rate

Revenue data limited

EPS Growth

+10.7% YoY

YoY Growth Rate

Steady EPS growth

R&D Spend

$56M/ year

Declining (-11% vs prior year)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

11.3%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~8 months

$50M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

Short runway — potential dilution ahead through share issuance

Cash watch

Fulcrum Therapeutics has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin
N/A
Data not available
Operating Margin
N/A
Data not available
ROCE
-6.5%
Weak — -6.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
-100.0%
Shrinking sales (-100.0% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
N/A
Data not available

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Stability

Debt / Equity
0.02
Conservative — low debt load (0.02)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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