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Iovance Biotherapeutics

IOVA
33
Biotechnology · Healthcare
Price
$5.00
+0.34 (+7.30%)
Market Cap
$1.79B
Exchange
NASDAQ
Winston Score
33
Winston is serious
Below-average fundamentals — multiple weak pillars.

Share count rising — dilution

+132.9% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 153.4M (2021) → 357.3M (2025)

Iovance Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing cancer immunotherapy products to harness the power of a patient's immune system to eradicate cancer cells. It has six ongoing phase 2 clinical studies, including C-144-01, of its lead product candidate, lifileucel, for the treatment of metastatic melanoma; C-145-04, of its product candidate lifileucel for recurrent, metastatic, or persistent cervical cancer; and C-145-03, of its produ

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+44.8% YoY

YoY Growth Rate

Strong revenue growth

EPS Growth

+47.2% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$300M/ year

Rising (+6% vs prior year)

114.0% of revenue

6.3x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

16.1%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~7 months

$197M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

Short runway — potential dilution ahead through share issuance

Strong grower

Iovance Biotherapeutics is growing revenue at 45% year-over-year. The Winston Score penalises unprofitable companies, but revenue at this pace tells a different story — this is a company still in "build mode."

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
98.6%
Premium pricing power — 98.6% gross margin
Operating Margin
-113.5%
Losing money on operations — -113.5%
ROCE
-10.5%
Weak — -10.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
+34.3%
Fast-growing sales (34.3% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-106.8%
Burning cash (-106.8%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.06
Conservative — low debt load (0.06)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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