Lyell Immunopharma

LYEL

Biotechnology · Healthcare

Price

$13.32

-0.57 (-4.10%)

Market Cap

$310.8M

Exchange

NASDAQ

Winston Score

Winston is worried

Weak fundamentals across most pillars.

Share count rising — dilution

+40.8% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 12.1M (2021) → 17.1M (2025)

Lyell Immunopharma, Inc., a T cell reprogramming company, engages in developing T cell therapies for patients with solid tumors. The company develops therapies using technology platforms, such as Gen-R, an ex vivo genetic reprogramming technology to overcome T cell exhaustion; and Epi-R, an ex vivo epigenetic reprogramming technology to generate population of T cells with durable stemness. Its pipeline includes LYL797, a T cell product candidate for the treatment of non-small cell lung cancer an

Winston Score History

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-71.4% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-511.1% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$159M/ year

↓ Declining (-8% vs prior year)

>1,000% of revenue

24486.9x the sector average (18%)

R&D spend declining — could signal cost-cutting or efficiency

Insider Activity

40.3%ownership

→ Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~7 months

$91M cash & investments

Quarterly Free Cash Flow

→ Burn rate stable

Short runway — potential dilution ahead through share issuance

Cash watch

Lyell Immunopharma has less than a year of cash at its current burn rate. Growth investors should watch for potential share dilution from future fundraising — that directly reduces your ownership.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin

-116500.0%

Thin — -116500.0% gross margin

Operating Margin

-2307850.0%

Losing money on operations — -2307850.0%

ROCE

-14.7%

Weak — -14.7% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY

-52.3%

Shrinking sales (-52.3% YoY)

EPS YoY

N/A

—

Data not available

EPS Consistency

0/8 quarters

Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion

N/A

—

Data not available

FCF Margin

-433609.7%

Burning cash (-433609.7%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity

0.14

Conservative — low debt load (0.14)

Interest Cover

N/A

—

Data not available

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Valuation

P/E Ratio (TTM)

N/M

—

Negative earnings — P/E not meaningful

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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