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Monte Rosa Therapeutics

GLUE
23
Biotechnology · Healthcare
Price
$24.56
+1.40 (+6.04%)
Market Cap
$1.60B
Exchange
NASDAQ
Winston Score
23
Winston is worried
Weak fundamentals across most pillars.

Share count rising — dilution

+78.5% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 46.5M (2021) → 83.1M (2025)

Monte Rosa Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. It develops an oral molecular glue degrader for GSPT1, a translational termination factor and degron-containing protein for the treatment of Myc-driven cancers. The company also develops CDK2 to treat ovarian, uterine, and breast cancers; NEK7 for the treatment of infl

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-95.0% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-219.3% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$142M/ year

Rising (+16% vs prior year)

114.4% of revenue

6.4x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

35.3%ownership

Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~12 months

$160M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Adequate runway but may need to raise capital within 2 years

Heavy R&D investment

Monte Rosa Therapeutics is putting 114% of revenue into R&D and that number is rising. That's 6.4x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
51.8%
Healthy — 51.8% gross margin
Operating Margin
-1188.5%
Losing money on operations — -1188.5%
ROCE
-8.9%
Weak — -8.9% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY
-73.1%
Shrinking sales (-73.1% YoY)
EPS YoY
-2757.1%
Earnings shrinking (-2757.1% YoY)

Earnings per share down more than 10%. Either a bad year, or a real decline.

EPS Consistency
0/8 quarters
Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-45.8%
Burning cash (-45.8%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.07
Conservative — low debt load (0.07)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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