Opus Genetics

IRD

Biotechnology · Healthcare

Price

$3.27

-0.01 (-0.30%)

Market Cap

$270.0M

Exchange

NASDAQ

Winston Score

Winston is worried

Below-average fundamentals — multiple weak pillars.

Based on the IPO prospectus (annual filing). This score will refine automatically once the company reports its first quarters.

Share count rising — dilution

+4089.3% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 14.9M (2021) → 622.2M (2025)

Opus Genetics, Inc., a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of unmet needs of patients with refractive and retinal eye disorders. The company offers Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as is in Phase III clinical trials for presbyopia and dim light or night vision disturbances. Its lead retinal product candidate is APX3330, a small-molecule inhibitor of reduction oxidation effect

Winston Score History

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-50.6% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-212.5% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$31M/ year

↑ Rising (+15% vs prior year)

217.0% of revenue

12.1x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

57.6%ownership

→ Flat

Insiders holding steady — not selling despite ability to

Cash Runway

~14 months

$60M cash & investments

Adequate runway but may need to raise capital within 2 years

Heavy R&D investment

Opus Genetics is putting 217% of revenue into R&D and that number is rising. That's 12.1x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin

100.0%

Premium pricing power — 100.0% gross margin

Operating Margin

-271.9%

Losing money on operations — -271.9%

ROCE

-251.5%

Weak — -251.5% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY

+29.1%

Fast-growing sales (29.1% YoY)

EPS YoY

N/A

Data not available

EPS Consistency

N/A

Data not available

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Cash Flow

Cash Conversion

N/A

—

Data not available

FCF Margin

-248.3%

Burning cash (-248.3%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity

0.00

Conservative — low debt load (0.00)

Interest Cover

N/A

Data not available

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Valuation

P/E Ratio (TTM)

N/M

—

Negative earnings — P/E not meaningful

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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