Orchestra BioMed Holdings

OBIO

Biotechnology · Healthcare

Price

$3.68

-0.04 (-1.08%)

Market Cap

$220.4M

Exchange

NASDAQ

Winston Score

Winston is worried

Below-average fundamentals — multiple weak pillars.

Share count rising — dilution

+87.7% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 20.4M (2021) → 38.4M (2025)

Orchestra BioMed Holdings, Inc. operates as a biomedical innovation company. The company's flagship product candidates include BackBeat Cardiac Neuromodulation Therapy (CNT) for the treatment of hypertension; and Virtue Sirolimus AngioInfusion Balloon (SAB) for the treatment of atherosclerotic artery disease. Its products also comprise FreeHold retractors that are minimally invasive surgical device solutions. The company has a strategic collaboration with Medtronic for the development and commer

Winston Score History

Growth Profile

For growth stock investors

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-87.3% YoY

YoY Growth Rate

Revenue declining

EPS Growth

+32.7% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$58M/ year

↑ Rising (+36% vs prior year)

173.8% of revenue

9.7x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

31.1%ownership

↑ Rising

Insiders increasing their stake — aligned with shareholders

Cash Runway

~4 months

$28M cash & investments

Quarterly Free Cash Flow

↓ Burn rate worsening

Short runway — potential dilution ahead through share issuance

Heavy R&D investment

Orchestra BioMed Holdings is putting 174% of revenue into R&D and that number is rising. That's 9.7x the sector average.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

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Quality

Gross Margin

16.4%

Thin — 16.4% gross margin

Operating Margin

-20069.1%

Losing money on operations — -20069.1%

ROCE

-42.7%

Weak — -42.7% return on capital

Negative ROIC means the business is losing money on every dollar invested in it.

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Growth

Sales YoY

+1033.9%

Fast-growing sales (1033.9% YoY)

EPS YoY

N/A

—

Data not available

EPS Consistency

2/8 quarters

Earnings rarely grow — volatile business

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Cash Flow

Cash Conversion

N/A

Data not available

FCF Margin

-168.3%

Burning cash (-168.3%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity

0.02

Conservative — low debt load (0.02)

Interest Cover

N/A

Data not available

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Valuation

P/E Ratio (TTM)

N/M

Negative earnings — P/E not meaningful

P/E vs Forward

N/A

not available

Data not available

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Dividends

Not applicable for this business.

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