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Sarepta Therapeutics

SRPT
29
Biotechnology · Healthcare
Also trades as: 0L35.L
Price
$18.03
-0.19 (-1.04%)
Market Cap
$1.90B
Exchange
NASDAQ
Winston Score
29
Winston is worried
Below-average fundamentals — multiple weak pillars.
Data as of Aug 12, 2026 · filings through Jun 30, 2026

Share count rising — dilution

+29.0% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 81.3M (2021) → 104.8M (2025)

Sarepta Therapeutics is a biotech company that makes medicines for rare genetic muscle diseases, mainly Duchenne muscular dystrophy (DMD). DMD is a severe condition that affects mostly young boys, causing progressive muscle weakness. Sarepta's main products include exon-skipping drugs like Exondys 51, Vyondys 53, and Amondys 45, as well as Elevidys, a gene therapy for DMD approved by the FDA in 2023.

Sarepta earns money by selling these prescription drugs to patients, primarily in the United States, though it is expanding internationally through partnerships. With a market cap of about $1.7 billion and a gross margin above 60%, the company has pricing power in a niche where few competitors exist. However, its operating margin is slightly negative, meaning it still spends heavily on research. The biggest growth driver is broader adoption of Elevidys, its gene therapy, but the main risk is that insurers may limit coverage due to the drug's very high price tag.

Winston Score History

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0 Congressional buys and 1 sell on SRPT in the last 12 months.

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Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

-34.3% YoY

YoY Growth Rate

Revenue declining

EPS Growth

-102.5% YoY

YoY Growth Rate

Earnings declining

R&D Spend

$1.5B/ year

Rising (+89% vs prior year)

69.2% of revenue

3.8x the sector average (18%)

Investing heavily in future products and technology

Insider Activity

10.4%ownership

Flat

Insider ownership roughly steady over the past year

Cash Runway

5+ years

Quarterly Free Cash Flow

→ Burn rate stable

$934M cash & investments at current burn rate

Heavy R&D investment

Sarepta Therapeutics is putting 69% of revenue into R&D and that number is rising. That's 3.8x the sector average. With 10+ years of cash runway, they have time to let it pay off.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

Every number that matters to educated investors.

Each metric is explained in plain language so you know exactly what you're looking at. Start your free trial now.

Quality

Gross Margin
62.8%
Premium pricing power — 62.8% gross margin
Operating Margin
3.3%
Thin — 3.3% operating margin
ROCE
0.6%
Weak — 0.6% return on capital

ROIC between 0% and 5%. They earn a few cents back per dollar invested in the business.

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Growth

Sales YoY
-20.4%
Shrinking sales (-20.4% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
4/8 quarters
Earnings inconsistent quarter-to-quarter

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Cash Flow

Cash Conversion
N/A
Data not available
FCF Margin
-6.7%
Burning cash (-6.7%)

Free cash flow is negative. They are burning cash, not generating it.

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Stability

Debt / Equity
0.55
Conservative — low debt load (0.55)
Interest Cover
N/A
Data not available

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Valuation

P/E Ratio (TTM)
N/M
Negative earnings — P/E not meaningful
P/E vs Forward
N/A
not available
Data not available

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Dividends

Not applicable for this business.
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