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Xeris Biopharma Holdings

XERS
58
Biotechnology · Healthcare
Price
$8.80
+0.11 (+1.27%)
Market Cap
$1.52B
Exchange
NASDAQ
Winston Score
58
Winston is curious
A decent business — some strong pillars, some weaker.

Share count rising — dilution

+118.6% over 4y

The company has issued more shares over this period, which dilutes each existing shareholder’s stake.

Diluted shares outstanding: 79.0M (2021) → 172.7M (2025)

Xeris Biopharma Holdings, Inc., a biopharmaceutical company, engages in developing and commercializing therapies for patient populations in endocrinology, neurology, and gastroenterology. The company markets Gvoke, a ready-to-use liquid glucagon for the treatment of severe hypoglycemia; and Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor proved for the treatment of endogenous hyper

Winston Score History

Growth Profile

When traditional metrics don't capture the full picture, these are the signals growth stock investors use instead.

Revenue Growth

+38.3% YoY

YoY Growth Rate

Revenue accelerating

EPS Growth

+121.7% YoY

YoY Growth Rate

EPS growth accelerating

R&D Spend

$31M/ year

Rising (+22% vs prior year)

10.7% of revenue

Below sector average (18%)

Investing heavily in future products and technology

Insider Activity

4.1%ownership

Declining

Insider ownership declining — could be dilution or selling

Cash Position

Cash flow positive

$112M cash & investments

Quarterly Free Cash Flow

↑ Burn rate improving

Company generates more cash than it spends — no dilution risk from fundraising

Revenue accelerating

Xeris Biopharma Holdings grew revenue 38% year-over-year and the growth rate is speeding up. That's the kind of momentum growth investors look for — the question is whether margins can follow.

The Winston Score above measures business quality today. Growth stocks often score lower because they invest in the future rather than maximising current profits. These metrics show what matters most for evaluating that future.

Score breakdown

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Quality

Gross Margin
84.0%
Premium pricing power — 84.0% gross margin
Operating Margin
9.5%
Modest — 9.5% operating margin
ROCE
15.7%
Strong — 15.7% return on capital

ROIC between 15% and 25%. Every dollar invested in the business earns 15 to 25 cents back per year.

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Growth

Sales YoY
+41.5%
Fast-growing sales (41.5% YoY)
EPS YoY
N/A
Data not available
EPS Consistency
6/8 quarters
Earnings grew in most of the last 8 quarters

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Cash Flow

Cash Conversion
404%
Turns 404% of profit into real cash
FCF Margin
15.0%
Converts sales into free cash efficiently (15.0%)

FCF margin between 10% and 20%. Every $100 in sales becomes $10 to $20 in real cash.

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Stability

Debt / Equity
2.87
Heavy debt load (2.87)
Interest Cover
1.25x
Dangerous — barely covers interest (1.3x)

Interest coverage between 1 and 3. Profits cover interest, but with little room to spare.

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Valuation

P/E Ratio (TTM)
124.3x
Expensive — P/E 124.3

P/E over 35. The market is pricing in heavy, sustained growth.

P/E vs Forward
+110.3
GROWING
Earnings expected to grow meaningfully — cheaper on forward P/E (124.3 → 14.0)

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Dividends

Not applicable for this business.
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